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SoTiSaR 2.0-NIS

Soft tissue tumours develop in the soft tissue of the body, such as muscles, fat tissue or ligaments. In the non-interventional study SoTiSaR 2.0-NIS, researchers collect and analyse data from patients with soft tissue tumours.

Soft tissue refers to fat, muscle, and connective tissue. Soft tissue tumours can occur anywhere in the body and comprise more than 150 subtypes. In children and adolescents, soft tissue tumours are the fifth most common type of tumour.

 

Why the study is needed

In SoTiSaR 2.0-NIS (Soft Tissue Sarcoma Registry, Non-Interventional Study), data from patients with a soft tissue tumour are collected and analysed. This includes information such as medical history, imaging, examination results, and treatment details.

Through this data collection, the researchers aim to gain deeper scientific insights into the disease, its progression, and its prognosis. They also intend to gather information on follow-up care, long-term effects, and quality of life. SoTiSaR 2.0-NIS thus provides a foundation of data for future clinical studies aimed at further optimising treatment.

The long-term goal is to improve the survival of patients with a soft tissue tumour and to identify the most effective targeted treatments. Future generations of patients will benefit from this.

 

Who can participate in the study

Children, adolescents, and adults with a soft tissue tumour can be included in the SoTiSaR 2.0-NIS. The study is non-interventional. This means that treatment continues as normal and no additional examinations are carried out. In Switzerland, it is expected that around 10–15 patients will take part in the study each year.

 

Who is responsible for the study

The international conduct of the non-interventional study is the responsibility of the Klinikum Stuttgart in Germany (sponsor). In Switzerland, the Swiss Paediatric Oncology Group (SPOG) is the sponsor representative responsible for SoTiSaR 2.0-NIS.

  • Swiss study lead: Dr. med. Willemijn Breunis, Consultant, University Children’s Hospital Zurich
  • Deputy Swiss study lead: PD Dr. med. Eva Brack, Consultant, Inselspital Bern

 

Contact details for the Swiss sponsor representative:

SPOG Coordination Centre

Partner Relations

Effingerstrasse 33

3008 Bern

Email: partnerrelations@spog.ch

Tel.: +41 31 389 91 89

In short

  1. As part of SoTiSaR 2.0-NIS, a wide range of data is collected from patients with a soft tissue tumour to deepen existing knowledge.
  2. The data collection serves as a basis for planning clinical studies for targeted treatments.
  3. The long-term goal is to improve the survival of future patients with a soft tissue tumour.

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Published 18.11.2025
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